Sucralose is an artificial sweetener that is used in place of natural sugar. Many people use sucralose as a substitute for sugar to control their weight. However, there may be several health risks associated with sucralose. Also, it is not clear whether sucralose actually helps people lose weight.
First, researchers in Australia did studies on rats and discovered that sucralose consumption caused shrinking of the thymus in rats. The thymus is an organ that is crucial to maintaining a healthy immune system; in humans it is particularly active in childhood. If sucralose has similar effects on humans, then long-term use of sucralose could cause harm to the immune system, especially in children.
Second, sucralose is created by replacing some of the atoms in natural sugar molecules with chlorine. This means sucralose belongs to a group of chemicals called organochlorines, which is another cause for concern. Organochlorines are known to be toxic to plants and animals, including humans. Some organochlorines are even used as pesticides. Sucralose is chemically similar to these toxic chemicals, so there may be a risk of poisoning if sucralose builds up in human body tissue (in fat tissue, for example).
Third, substituting artificial sweeteners for real sugar in coffee, tea, and soft drinks often does not help people lose weight, since it reinforces the habit of enjoying sweet food. When people use artificial sweeteners in their drinks, their appetite for sugar remains strong, and they satisfy their sweetness cravings by eating greater portions of foods containing real sugar, such as cakes or cookies. Such eating habits can prevent them from achieving their goal of losing weight.